Final meeting of the 2020 - 2021 VDC season.

Virtual VDC
MONDAY
May 10, 2021

Focus:
Public Health Policy, Ethics, and Challenges
Count Me In! Click Here to Register

Five Lessons Learned:
The Science and Tribulations of Adenovirus-vector Vaccines for COVID


1. There Is No Magic Bullet

The advantages and disadvantages of mRNA vaccines (e.g. Pfizer; Moderna) compared to adenovirus-vector vaccines (e.g. Johnson & Johnson; AstraZenica)

Paul A. Offit, MD

Director, Vaccine Education Center, CHOP
Maurice R. Hilleman Professor of Vaccinology,
Perelman School of Medicine, University of Pennsylvania



2. The System Worked Exactly As It Should

How the CDC rapidly red flagged and acted on a
potentially lethal, 1 in a million side effect

3. ACIP Says Yes But...

Processes and outcomes of the Friday, April 23, 2021 Emergency Meeting of the CDC's Advisory Committee on Immunization Practice (ACIP).

Sara E. Oliver, MD, MSPH

Medical Officer, CDC
CDC National Center for Immunization and Respiratory Diseases (NCIRD)
Lead, ACIP COVID-19 Vaccine Work Group



4. Blood Clots Will Continue To Be A Rare Risk

What we currently know abut coagulation causes, risk-screening, and treatment for thrombosis events associated with J&J and AstraZenica vaccines

Nigel Key, MD

Vice Chief for Research, Division of Hematology, UNC Chapel Hill
Director, UNC Blood Research Center
Expert, Arterial and Venous Thromboembolic Disorders



5. There Is No "One Right Path" Forward

The ethical issues facing governments and organizations tasked with making risk / benefit decisions about using adenovirus-vector vaccines.

Arthur L. Caplan, PhD

Drs. William F. and Virginia Connolly Mitty Professor of Bioethics, Department of Population Health
NYU Grossman School of Medicine



Q&A

Pre-submitted and real-time questions for the panelists

Carlos del Rio MD

Executive Associate Dean,
Emory School of Medicine & Grady Health System
Ex Officio Member, Committee on Human Rights,
The National Academies of Sciences, Engineering, and Medicine
Foreign Secretary, National Academy of Medicine



Clubhouse Location:
A Zoom screen near you
Agenda: (All times are ET)
5:25pm - Hall opens
5:30pm - Cowbell rings, meeting brought to order
7:00pm - Q&A
7:30pm - Adjourn



Dear Vacciners,
Lesson learned … Never say never.

I know that I've said -- a couple of times at least -- that we were done, Done, DONE with COVID-related VDC meetings for the year but incredibly interesting, super timely opportunities to take advantage of world famous scientists' deep knowledge (and even deeper desire to earn their very own Vaccine Dinner Club speaker's mug) just keep popping up.

And it happened again this month.

Specifically, on April 13, 2021 the CDC and the FDA recommended pausing the rollout of the Johnson & Johnson vaccine after multiple cases of potentially lethal blood clots were identified through the CDC's Vaccine Adverse Events Reporting System. (Go VAERS!)

So naturally VDC central sprang into action.

One hundred seventy nine emails later (true story, I've been keeping count) we have identified the perspectives we want to address and assembled an absolutely world class line up of presenters. As you can see from the agenda, these include Paul Offit (eternal winner of the Best Vaccine Explainer Ever award), Sara Oliver (presenter and participant in last Friday's emergency ACIP meeting that voted to restart the J&J rollout), Nigel Key (international expert in the ultra-rare type of blood clots that adenovirus-vector vaccines seem to be causing), and Art Caplan (intrepid explorer of the bioethical minefield we call the vaccine rollout).

Put them all together and what do you have? A spectacular finish to the 2020-2021 season of the Virtual Vaccine Dinner Club, that's what!

So register now and spread the word.

Be there or risk being left in the dark*
-Kimbi Hagen
VDC Director/Goddess

*This is a reference to our lame science joke of the month, found at the very bottom of the VDC registration confirmation page. Register now and check it out!"