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Virology and Molecular Biomarkers Core Specific Aims
- Expand the range of existing assays for quantification of all aspects of SIV/SHIV infection and replication that are essential to the study of AIDS pathogenesis, therapy, and prevention in non-human primates.
Rationale: The continued growth and innovation of HIV/AIDS research in nonhuman primates requires standardized and novel assays for measuring diverse viruses, viral forms, and virus-host interactions
- Expand the menu of tests needed to support clinical studies/trials of HIV-1 infections and coinfections, provide testing in a CLIA certified laboratory, and provide economy of scale through provision of shared resources.
Rationale: Clinical, translational, and behavioral studies of HIV-1 infection and co-infections require a multitude of tests for the detection and quantification of an array of pathogens
- Provide training and technical and intellectual support to local, national, and international AIDS research efforts that include nonhuman primates and/or human infections.
Rationale: The training and scientific support of a new generation of HIV/AIDS researchers is essential for the success of HIV/AIDS research programs in the Emory community and across the globe.
- Facilitate academic and industrial development of novel AIDS therapy and prevention programs through the provision of virological services.
Rationale: The viral and gene expression quantification offered through this Core is essential for the evaluationof the effectiveness of any potential therapy or prevention program.