Virology and Molecular Biomarkers Core Specific Aims
Expand the range of existing assays for quantification of all aspects of SIV/SHIV infection and replication that are essential to the study of AIDS pathogenesis, therapy, and prevention in non-human primates. Rationale: The continued growth and innovation of HIV/AIDS research in nonhuman primates requiresstandardized and novel assays for measuring diverse viruses, viral forms, and virus-host interactions
Expand the menu of tests needed to support clinical studies/trials of HIV-1 infections and coinfections,provide testing in a CLIA certified laboratory, and provide economy of scale throughprovision of shared resources. Rationale: Clinical, translational, and behavioral studies of HIV-1 infection and co-infections require a multitudeof tests for the detection and quantification of an array of pathogens
Provide training and technical and intellectual support to local, national, and international AIDS research efforts that include nonhumanprimates and/or human infections. Rationale: The training and scientific support of a new generation of HIV/AIDS researchers is essential for the success of HIV/AIDS research programs in the Emory community and across the globe.
Facilitate academic and industrial development of novel AIDS therapy and prevention programs through the provision of virological services. Rationale: The viral and gene expression quantification offered through this Core is essential for the evaluationof the effectiveness of any potential therapy or prevention program.